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The physiological action this alkaloid and that atropine closely resemble each other that they are said some high authorities qualitatively identical. Slight discrepancies in their action are accounted for the difficulty obtaining the hyoscyamia in a state purity.

There seems abundant evidence, however, that, notwithstanding their great similarity, hyoscyamine exercises a much more marked hypnotic effect thesis statistics upon the cerebrum. In other respects, except the dose, the reader will find an account its action under the head Atropine.

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The dose sometimes considerably larger.

Hyoscyamine may used for the same purpose as atropine, but has also been employed as a hypnotic or sedative in conditions excitement, as in mania also in paralysis agitans, chorea, locomotor ataxia, and tetanus.

Unfortunately, even yet, hyoscyamine liable vary considerably in strength, or rather, purity, and consequently statements as the effects similar doses will exhibit decided discrepancies. and Atropina may consulted.

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It differs but very slightly from belladonna, except in its greater tendency produce sleep. Poisoning from treated in the same way as that from belladonna. Even the increased hypnotic tendency not always observed, since a talkative and restless delirium described as occurring in many cases. The preparations henbane are the most uncertain strength, that the effective dose the extract no longer officinal ranged from two two hundred and fifty grains. The present alcoholic extract, made from recent leaves, much more efficient.

The quantities frequently prescribed as corrigent in cathartic pills are probably no more value than any inert extract which might used as an excipient.

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